Author

Michael McMillan

University of Michigan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Sami J. BarmadaiD· 2 shared Caroline Hsieh· 1 shared Christopher J. DonnellyiD· 1 shared Daniela C. ZarnescuiD· 1 shared Danielle de Paula MoreiraiD· 1 shared Dominic L. JulianiD· 1 shared Elizabeth M.H. TankiD· 1 shared Eric B. AlsopiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersNeuroscience

Sami J. BarmadaORCID

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2 papers

Recent·Most cited

ADAR2-Mediated RNA Editing Promotes TDP-43 Nuclear Export and Alters RNA Binding

Stephen R. Moore, Dominic L. Julian, Eric B. Alsop, Lauren M. Gittings, Ileana Lorenzini, Michael McMillan, Sam Macklin-Isquierdo, Erik M. Lehmkuhl, Petr Kaláb, Danielle de Paula Moreira, Lindsey R. Hayes, Christopher J. Donnelly, Sami J. Barmada, Daniela C. Zarnescu, Kendall R. Van Keuren‐Jensen, Rita Sattler

This study shows ADAR2-mediated RNA editing promotes TDP-43 nuclear export and alters its RNA binding, contributing to neurodegenerative disease mechanisms.

bioRxiv · Jun 25, 2026 · PreprintNeuroscience

RNA methylation influences TDP43 binding and disease pathogenesis in models of amyotrophic lateral sclerosis and frontotemporal dementia

Michael McMillan, Nicolás Gómez, Caroline Hsieh, Michael E. Bekier, Xingli Li, Roberto Miguez, Elizabeth M.H. Tank, Sami J. Barmada

This study shows that RNA methylation influences TDP43 binding and contributes to neurodegeneration in ALS by modulating RNA stability and TDP43 function.

Molecular Cell · Jan 1, 2023Peer-reviewedNeuroscience