Author

Sam Wein

University of Tübingen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Organism:human· 2 Assay:metagenomics· 2 Assay:proteomics· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Stefanie KaiseriD· 3 shared Jan Felix Dalwigk· 2 shared Jannick Schicktanz· 2 shared Kira Kerkhoff· 2 shared Leona A. RuslingiD· 2 shared Michael S. DeMottiD· 2 shared Nur Yeşiltaç-TosuniD· 2 shared Oskar Knittelfelder· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

Stefanie KaiserORCID

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Author profile →

3 papers

Recent·Most cited

Harmonized nucleoside mass spectrometry enables reproducible cross-platform RNA modification quantification

Jan Felix Dalwigk, Kira Kerkhoff, Oskar Knittelfelder, Robert L. Ross, Maria Cristina Petrella, Anna Kuśnierczyk, Tulsi Bhandari, Aurore Attina, Alicia Burkard, Carolina Brás Costa, Michael S. DeMott, K J. Johnson, Xenia Kerkhoff-Bernaciak, Jennifer Kist, Ken Kögel, , Stefanie Kaiser

The paper benchmarks cross-platform RNA modification quantification using LC-MS/MS and finds that harmonized workflows and SILIS normalization improve reproducibility across different instrument types.

bioRxiv · Jul 23, 2026 · PreprintGenomics

Human 28S rRNA analysed by state-of-the-art oligonucleotide mass spectrometry: benchmarking current capabilities and a call to action for MS-Seq

Jannick Schicktanz, Ying Qi, Junzhou Wu, Bibek Hamal, Antony Lechner, Sam Wein, Oskar Knittelfelder, Nur Yeşiltaç-Tosun, Jan Felix Dalwigk, Katharina Hoja, Leona A. Rusling, Sofia Obersteiner, Ella Bellenberg, Kira Kerkhoff, Michael S. DeMott, , Stefanie Kaiser

The paper benchmarks MS-Seq for human 28S rRNA analysis, showing reproducible results across platforms but highlighting gaps in coverage and ambiguity.

bioRxiv · Jul 17, 2026 · PreprintMolecular Biology

Ion-Pair-Free Nanoflow HILIC-MS With RNase Benchmarking for Native RNA

Ying Qi, Chengkang Li, Nur Yeşiltaç-Tosun, Jannick Schicktanz, Leona A. Rusling, Steffen Kaiser, Sam Wein, Stefanie Kaiser

The paper introduces a sensitive oligonucleotide-MS workflow for analyzing native RNA modifications and benchmarks three nucleases for their ability to cleave modified RNAs.

bioRxiv · Nov 18, 2025 · PreprintMolecular Biology