Author

Samuel Chung

Primary ORCID profile (0000-0003-2553-1396 · 6 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Samuel ChungiD6 papers · Northeastern University

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Carlos Gil· 2 shared Chloe Robinson· 2 shared Gemma Gatti· 2 shared George Kiloh· 2 shared Ioannis KasioulisiD· 2 shared Lia PanmaniD· 2 shared Magdalena Łukasiak· 2 shared Nikolaos NikolaouiD· 2 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Carlos Gil

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2 papers

Recent·Most cited

iPSC-derived hepatocytes accurately recapitulate population diversity in alpha-1-antitrypsin deficiency and offer a novel in vitro model for large-scale drug efficacy screening studies.

Carlos Gil, Vanesa Papastavrou, Gemma Gatti, Samuel Chung, George Kiloh, Ka Chun Cheung, Magdalena Łukasiak, Chloe Robinson, Lia Panman, Ioannis Kasioulis, Nikolaos Nikolaou

This study generates iPSC-derived hepatocytes from A1ATD donors and shows they recapitulate disease features and respond to drug treatments, offering a model for drug screening.

bioRxiv · Jan 21, 2025 · PreprintCell Biology

Development of optimised human iPSC-derived hepatocytes with improved liver function for in vitro metabolic disease modelling and toxicity studies

Magdalena Łukasiak, Gemma Gatti, Samuel Chung, George Kiloh, Chloe Robinson, Ioannis Kasioulis, Carlos Gil, Lia Panman, Nikolaos Nikolaou

This paper develops optimised human iPSC-derived hepatocytes (Opti-HEP) with improved liver function for metabolic disease modelling and toxicity studies, showing comparable functionality to primary human hepatocytes.

bioRxiv · Nov 18, 2024 · PreprintCell Biology