Author

Ioannis Kasioulis

University of DundeeORCID 0000-0001-5054-5357Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Carlos Gil· 2 shared Chloe Robinson· 2 shared Gemma Gatti· 2 shared George Kiloh· 2 shared Lia PanmaniD· 2 shared Magdalena Łukasiak· 2 shared Nikolaos NikolaouiD· 2 shared Samuel Chung· 2 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

Carlos Gil

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintJan 21, 2025

iPSC-derived hepatocytes accurately recapitulate population diversity in alpha-1-antitrypsin deficiency and offer a novel in vitro model for large-scale drug efficacy screening studies.

Carlos Gil, Vanesa Papastavrou, Gemma Gatti…·Nikolaos Nikolaou

This study generates iPSC-derived hepatocytes from A1ATD donors and shows they recapitulate disease features and respond to drug treatments, offering a model for drug screening.

1 citation

humanscRNA-seq

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Cell BiologybioRxivPreprintNov 18, 2024

Development of optimised human iPSC-derived hepatocytes with improved liver function for in vitro metabolic disease modelling and toxicity studies

Magdalena Łukasiak, Gemma Gatti, Samuel Chung…·Nikolaos Nikolaou

This paper develops optimised human iPSC-derived hepatocytes (Opti-HEP) with improved liver function for metabolic disease modelling and toxicity studies, showing comparable functionality to primary human hepatocytes.

1 citation

humanscRNA-seq

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Developmental BiologyJournal of Cell SciencePeer-reviewedFeb 25, 2022

A lateral protrusion latticework connects neuroepithelial cells and is regulated during neurogenesis

Ioannis Kasioulis, Alwyn Dady, John L. James…·Kate G. Storey

The paper identifies and characterizes lateral protrusions in neuroepithelial cells, showing they form a latticework regulated by WAVE1 and are involved in neurogenesis.

13 citations

experimental assay

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