Author

Samuel J. Watson

University of Cambridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Aneisha Duggal· 1 shared Christian M. Gawden‐BoneiD· 1 shared Claudia Melucci· 1 shared Guinevere L. Grice· 1 shared James A. NathaniD· 1 shared James C. WilliamsoniD· 1 shared Nicholas J. MathesoniD· 1 shared Niek WitiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Aneisha Duggal

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1 paper

Recent·Most cited

Regulation of proteasome activation by a ubiquitin-independent feedback mechanism

Samuel J. Watson, James C. Williamson, Pehuén Pereyra Gerber, Guinevere L. Grice, Claudia Melucci, Aneisha Duggal, Christian M. Gawden‐Bone, Niek Wit, Richard T. Timms, James A. Nathan, Nicholas J. Matheson, Paul J. Lehner

This study identifies ZFAND5/6 as ubiquitin-independent proteasome activators that regulate NF-κB signaling by degrading UBCH5c.

bioRxiv · Jun 9, 2026 · PreprintBiochemistry