Sandeep K. Rai

The regulation of virulence gene expression is controlled by phase separation of heterochromatin protein 1 (HP1) in Plasmodium falciparum

This study shows that PfHP1 phase separation controls var gene silencing in P. falciparum by forming heterochromatin clusters, leading to antigenic variation.

Chaperone-mediated heterotypic phase separation prevents the amyloid formation of the pathological Y145Stop variant of the prion protein

This study shows that Ydj1, an Hsp40, prevents amyloid formation of the Y145Stop prion protein variant through heterotypic phase separation.