Till Steffen Voss

This study identifies three druggable targets in Plasmodium falciparum gametocytes using high-throughput screening and reveals resistance mechanisms for one compound.

This study shows that CHIR-124, a human Chk1 inhibitor, is active against Plasmodium falciparum through dual inhibition of PfArk1 and hemozoin formation, suggesting polypharmacology as a strategy for antimalarial drugs.

This study identifies PfJmjC1 as a key regulator of heterochromatin organization in Plasmodium falciparum, showing its role in genome architecture and parasite life cycle.

This study shows that PfHP1 phase separation controls var gene silencing in P. falciparum by forming heterochromatin clusters, leading to antigenic variation.

The paper develops an in vitro and in vivo platform for testing malaria transmission-blocking drugs using engineered Plasmodium falciparum gametocytes and humanized mice.

This study shows that PfSET10 is not required for var gene expression, antigenic variation, or blood stage parasite survival.

The paper investigates the spatiotemporal roles of three Aurora-related kinases in Plasmodium falciparum mitosis and gametogenesis, revealing distinct functions in cell division processes.