Serial Imaging of Tumour and microEnvironment (SITE) platform for live-cell ex vivo modelling of primary and metastatic cancer dynamics
Vaibhav Murthy, Rawan Makkawi, Francis Anderson, Carol M. R. Halsey, Elise C. Manalo, Sanjay Srikanth, Gabriella Tangkilisan, Ting Zheng, James C. McGann, Marc R. Birtwistle, Jeremy Copperman, Alexander E. Davies
The paper introduces the SITE platform for live-cell ex vivo modeling of cancer and TME interactions, revealing tissue-specific dynamics and ERK signaling patterns in breast cancer.
bioRxiv · Sep 8, 2025 · PreprintCancer Biology