Author

Sara Espinoza

Cedars-Sinai Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Nicolas MusiiD· 2 shared Aaron Gouw· 1 shared Adam Lowe· 1 shared Alejandro PenaiD· 1 shared Alex ClaiborneiD· 1 shared Alicia Belangee· 1 shared Andrew Hepler· 1 shared Andrew JonesiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersSystems Biology

Nicolas MusiORCID

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2 papers

Recent·Most cited

Molecular Transducers of Physical Activity Consortium (MoTrPAC): Initial Insights into the Dynamic Human Responses to Exercise

MoTrPAC Study Group, Anna R. Brandt, Jerome Fleg, Bret H. Goodpaster, Byron C. Jaeger, Christopher A. Jin, Neil Michael Johannsen, Daniel H. Katz, Hasmik Keshishian, Wendy M. Kohrt, William E. Kraus, Bridget E. Lester, Edward L. Melanson, Michael E. Miller, Samuel Montalvo, , Jessica L. Rooney

The paper presents initial findings from the MoTrPAC consortium, showing that acute and chronic exercise induce distinct physiological and molecular responses, with chronic training improving key health metrics.

bioRxiv · Oct 1, 2026 · PreprintSystems Biology

A human and mouse subpopulation of senescent β-cells induces pathologic dysfunction through targetable paracrine signaling

Kanako Iwasaki, Priscila Carapeto, Cristian Abarca, Francesko Hela, Stephanie Sanjines, Sebastian Pena, Sandra M. Le, Hui Pan, Christopher Cahill, Ayush D. Midha, Juliana Alcoforado Diniz, Dylan S. Baker, Sergii Domanskyi, Sara Espinoza, Alejandro Pena, , Cristina Aguayo‐Mazzucato

The paper identifies senescent β-cell subpopulations in humans and mice that induce pathologic dysfunction through paracrine signaling and shows JAK inhibitors can reverse this effect.

bioRxiv · May 7, 2025 · PreprintDevelopmental Biology