Author

Sarah C. Hales

Montreal Clinical Research Institute

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Neuroscience· 1

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Christine JolicoeuriD· 1 shared Deniz DalkaraiD· 1 shared Jenny Cai· 1 shared Katarina Stevanovic· 1 shared Marine LacommeiD· 1 shared Mélissa DesrosiersiD· 1 shared Michel CayouetteiD· 1 shared Thérence Bois· 1 shared

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2022-2022 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperNeuroscience

Christine JolicoeurORCID

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1 paper

Recent·Most cited

NeuroscienceScience AdvancesPeer-reviewedOct 19, 2022

Numb reduces Tau levels and prevents neurodegeneration in mouse models of tauopathy in an isoform-specific manner

Marine Lacomme, Sarah C. Hales, Thomas W. Brown…·Michel Cayouette

This study shows that Numb regulates Tau levels and prevents neurodegeneration in tauopathy models, with Numb-72 specifically reducing intracellular Tau.

18 citations

mouseexperimental assay

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