Author

Thomas W. Brown

Montreal Clinical Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1 Approach:statistical model· 1

Frequent Co-Authors

Michel CayouetteiD· 3 shared Christine JolicoeuriD· 2 shared Aline Giselle Rangel Olguin· 1 shared Arjun KrishnaswamyiD· 1 shared Awais JavediD· 1 shared Benoît BoulaniD· 1 shared Camille Boudreau‐Pinsonneault· 1 shared Catherine Theriault· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersNeuroscience

Michel CayouetteORCID

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3 papers

Recent·Most cited

Cadherin 4 assembles a family of color-selective retinal circuits that respond to light offset.

Aline Giselle Rangel Olguin, Pierre‐Luc Rochon, Catherine Theriault, Thomas W. Brown, Michel Cayouette, Erik P. Cook, Arjun Krishnaswamy

This study identifies cadherin 4 as a key molecule for layer-specific targeting of retinal ganglion cells in sublaminae 1 and 3a, affecting their connectivity and visual responses.

bioRxiv · May 8, 2024 · PreprintNeuroscience

Pou3f1 orchestrates a gene regulatory network controlling contralateral retinogeniculate projections

Michel Fries, Thomas W. Brown, Christine Jolicoeur, Benoît Boulan, Camille Boudreau‐Pinsonneault, Awais Javed, Pénélope Abram, Michel Cayouette

This study identifies Pou3f1 as a master regulator of contralateral retinogeniculate projections by controlling a gene regulatory network in developing mouse retinal ganglion cells.

Cell Reports · Aug 1, 2023Peer-reviewedDevelopmental Biology

Numb reduces Tau levels and prevents neurodegeneration in mouse models of tauopathy in an isoform-specific manner

Marine Lacomme, Sarah C. Hales, Thomas W. Brown, Katarina Stevanovic, Christine Jolicoeur, Jenny Cai, Thérence Bois, Mélissa Desrosiers, Deniz Dalkara, Michel Cayouette

This study shows that Numb regulates Tau levels and prevents neurodegeneration in tauopathy models, with Numb-72 specifically reducing intracellular Tau.

Science Advances · Oct 19, 2022Peer-reviewedNeuroscience