HpBoRB, a helminth-derived CCP domain protein which binds RELMβ
Vivien Shek, Abhishek Jamwal, Danielle J. Smyth, Tania G. Frangova, Alice R Savage, Sarah Kelly, Gavin James Wright, Rachel L. Toth, Erich M. Schwarz, Rick M. Maizels, Matthew K. Higgins, Alasdair C. Ivens, Hermelijn H. Smits, Henry J. McSorley
The paper identifies a helminth-derived CCP domain protein, HpBoRB, that binds RELMβ, a host protein with anti-helminth properties, suggesting a mechanism of immune evasion.
International Journal for Parasitology · Sep 24, 2025Peer-reviewedImmunology