Author

Tania G. Frangova

University of Dundee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:proteomics· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Henry J. McSorleyiD· 4 shared Danielle J. SmythiD· 3 shared Abhishek JamwaliD· 2 shared Alice R SavageiD· 2 shared Florent Colomb· 2 shared Gavin James WrightiD· 2 shared Matthew K. HigginsiD· 2 shared Nicole W. P. Ong· 2 shared

Activity by Year

2024-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersImmunology

Henry J. McSorleyORCID

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4 papers

Recent·Most cited

Transcriptomic and proteomic analysis show minimal role formast cell ST2 in primary Heligmosomoides polygyrus bakeriinfection

Nicole W. P. Ong, Suzanne H. Hodge, Christa P. Baker, Danielle J. Smyth, Tania G. Frangova, Henry J. McSorley

This paper investigates the role of mast cell ST2 in Heligmosomoides polygyrus bakeri infection using transcriptomic and proteomic analysis, finding minimal impact on infection outcomes.

bioRxiv · Nov 3, 2025 · PreprintImmunology

HpBoRB, a helminth-derived CCP domain protein which binds RELMβ

Vivien Shek, Abhishek Jamwal, Danielle J. Smyth, Tania G. Frangova, Alice R Savage, Sarah Kelly, Gavin James Wright, Rachel L. Toth, Erich M. Schwarz, Rick M. Maizels, Matthew K. Higgins, Alasdair C. Ivens, Hermelijn H. Smits, Henry J. McSorley

The paper identifies a helminth-derived CCP domain protein, HpBoRB, that binds RELMβ, a host protein with anti-helminth properties, suggesting a mechanism of immune evasion.

International Journal for Parasitology · Sep 24, 2025Peer-reviewedImmunology

Vaccination against helminth IL-33-modulators permits immune-mediated parasite ejection

Danielle J. Smyth, Suzanne H. Hodge, Nicole W. P. Ong, Josh Richards, Florent Colomb, Samuele Di Carmine, Vivien Shek, Tania G. Frangova, Marta Campillo Poveda, Rick M. Maizels, Henry J. McSorley

This paper shows that vaccinating against helminth IL-33-modulators can protect against infection by reversing immunosuppression and enhancing Th2 immunity.

Cell Reports · May 1, 2025Peer-reviewedImmunology

Heparan sulphate binding controls in vivo half-life of the HpARI protein family

Florent Colomb, Abhishek Jamwal, Adefunke Ogunkanbi, Tania G. Frangova, Alice R Savage, Sarah A. Kelly, Gavin James Wright, Matthew K. Higgins, Henry J. McSorley

The paper shows that DNA and heparan sulphate binding prolongs the in vivo half-life of HpARI1 and HpARI2 proteins compared to HpARI3.

eLife · Aug 27, 2024Peer-reviewedImmunology