Inhibition of Ribosome Biogenesis in vivo Causes p53-Dependent Death and p53-Independent Dysfunction
Charles J. Cho, Thanh Nguyen, Amala K Rougeau, Yang‐Zhe Huang, Sarah To, Xiaobo Lin, Supuni Thalalla Gamage, Jordan L. Meier, Jason C. Mills
This study investigates the effects of ribosome biogenesis inhibition in vivo by deleting Nat10 in mice, revealing p53-dependent and -independent consequences on acinar cell function and tumorigenesis.
Cellular and Molecular Gastroenterology and Hepatology · Jan 1, 2025Peer-reviewedCell Biology