Charles J. Cho

This study identifies IFRD1 as a ribosome-salvaging factor that stabilizes non-translating 80S ribosomes during ER stress, preventing degradation and cell death.

This study investigates the effects of ribosome biogenesis inhibition in vivo by deleting Nat10 in mice, revealing p53-dependent and -independent consequences on acinar cell function and tumorigenesis.

This study identifies IFRD1 as a key regulator of ER stress and urothelial homeostasis in mice, showing its role in maintaining bladder function and preventing cell shedding.