Author

Sean Brazil

Trinity College Dublin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:host-pathogen & immune response· 2 Organism:Arabidopsis· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Organism:fungi (other)· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Johannes WageneriD· 2 shared Dominik Ruf· 1 shared Hesham Elsaman· 1 shared Isabel Kopp-Fouquet· 1 shared Kalpana SinghiD· 1 shared Karl DichtliD· 1 shared Kristina Striegler· 1 shared Liyanage Devthilini Pasasum FernandoiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

Johannes WagenerORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Rho2-dependent cell wall remodeling boosts the fungistatic activity of manogepix against Aspergillus fumigatus

Sean Brazil, Isabel Kopp-Fouquet, Samuel Zen Kai Yap, Michael Carty, Johannes Wagener

This study shows that Rho2-dependent cell wall remodeling enhances manogepix's fungistatic effect against Aspergillus fumigatus by reducing cell wall chitin upregulation.

The Cell Surface · Dec 14, 2025Peer-reviewedMicrobiology

Rho2 regulates granulocyte-triggered stress adaptation and cell wall remodeling in Aspergillus fumigatus

Dominik Ruf, Kristina Striegler, Sean Brazil, Hesham Elsaman, Kalpana Singh, Mathieu Lepas, Liyanage Devthilini Pasasum Fernando, Victor Brantl, Patricia Heß, Karl Dichtl, Vishukumar Aimanianda, Tuo Wang, Johannes Wagener

This study shows Rho2 in Aspergillus fumigatus enhances cell wall remodeling and stress resistance against granulocyte attacks, improving survival through upregulation of cell wall biosynthesis.

Microbiological Research · May 23, 2025Peer-reviewedMicrobiology