Hippocampal mGluR5 levels are comparable in Alzheimer's and control brains, and divergently influenced by amyloid and tau in control brain
Junlong Wang, Serena Savodalli, Yanyan Kong, Cinzia Maschio, Uwe Konietzko, Jan Klohs, Daniel Razansky, Axel Rominger, Linjing Mu, Roger Schibli, Christoph Höck, Roger M. Nitsch, Ruiqing Ni
This study finds no difference in hippocampal mGluR5 levels between Alzheimer's and control brains, but shows amyloid and tau have opposing effects on mGluR5 in controls.
bioRxiv · May 25, 2024 · PreprintNeuroscience