Author

Seth Allen

Scripps Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Jeffery W. KellyiD· 2 shared Benjamin F. CravattiD· 1 shared Carl T. AshiD· 1 shared Daniel SerwasiD· 1 shared Daniella A. Yacoubian· 1 shared Danny Garza· 1 shared David A. AgardiD· 1 shared Elizabeth A. MontabanaiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

Jeffery W. KellyORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Intralysosomal Amyloidogenesis and Proximity Labeling by Cathepsin C

Ruben D. Elias, Seth Allen, Idil Itir Demiralp, Robert T. O'Neill, Jan-Hannes Schäfer, Hannah Siems, Elizabeth A. Montabana, Utz H. Ermel, Carl T. Ash, Fatema Abdurrob, Daniella A. Yacoubian, Oren L. Lederberg, Daniel Serwas, David A. Agard, Benjamin F. Cravatt, Jeffery W. Kelly

This study identifies two mechanisms by which dipeptide esters disrupt lysosomal homeostasis: amyloid fibril formation and proximity labeling via Cathepsin C.

bioRxiv · Jul 7, 2026 · PreprintBiochemistry

A HaloTag-4R-Tau Pulse-Chase Sensor Reveals Neddylation Inhibition Promotes Degradation of Tau in iNeurons

Qiang Xiao, Zi Gao, Seth Allen, Danny Garza, Richard I. Morimoto, Jeffery W. Kelly

The paper develops a HaloTag-4R-Tau sensor to study tau clearance in iNeurons and identifies Neddylation inhibition as a method to promote tau degradation.

bioRxiv · Jan 29, 2026 · PreprintNeuroscience