SHIP1 regulates TREM2 signalling and macrophage functions in a hiPSC-derived model
Claire Martin, Juliane Obst, Shania Ibarra, Emma J. Murphy, Katerina Gospodinova, Emma Mead
This study shows that SHIP1 regulates TREM2 signaling and macrophage functions in hiPSC-derived macrophages, affecting inflammation and phagocytosis.
bioRxiv · Jul 2, 2025 · PreprintImmunology