Epigenetic gene silencing by heterochromatin primes fungal resistance
Sito Torres-Garcia, Imtiyaz Yaseen, Manu Shubhdarshan Shukla, Pauline N. C. B. Audergon, Sharon A. White, Alison L. Pidoux, Robin C. Allshire
The paper shows that caffeine induces epigenetic resistance in fission yeast through heterochromatin silencing, which can lead to cross-resistance to fungicides.
Nature · Sep 9, 2020Peer-reviewedGenetics