Molecular BiologybioRxivPreprint
Castling, a novel therapeutic concept for rewiring pathological gene-expression networks, enabled by the TRIPLE technology
Dinu Antony, Maria Silvia Roman Azcona, Hagar Kalinski…·Claudio Mussolino
The paper introduces a therapeutic strategy called castling to correct gene-expression imbalances by rewiring miRNA regulation using the TRIPLE genome-editing technology.
DOI 10.64898/2026.01.28.702195