Author

Dinu Antony

Radboud University Nijmegen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2 Genetic & Genomic Medicine· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Miriam SchmidtsiD· 2 shared Philip L. BealesiD· 2 shared Zeineb Bakey· 2 shared Aaron Day-Williams· 1 shared Abigail O. SmithiD· 1 shared Aileen Reghan FoleyiD· 1 shared Allan Daly· 1 shared Andreas B. DiendorferiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Miriam SchmidtsORCID

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Author profile →

4 papers

Recent·Most cited

Castling, a novel therapeutic concept for rewiring pathological gene-expression networks, enabled by the TRIPLE technology

Dinu Antony, Maria Silvia Roman Azcona, Hagar Kalinski, Marianne Pultar, Swetlana Adamsky, Sharon Avkin Nachum, Eyal Shalom, Manuel Rhiel, Andreas Tsouris, Andreas B. Diendorfer, Geoffroy Andrieux, Melanie Boerries, Matthias Hackl, Tatjana I. Cornu, Daniel Zurr, , Claudio Mussolino

The paper introduces a therapeutic strategy called castling to correct gene-expression imbalances by rewiring miRNA regulation using the TRIPLE genome-editing technology.

bioRxiv · Feb 19, 2026 · PreprintMolecular Biology

IFT74 variants cause skeletal ciliopathy and motile cilia defects in mice and humans

Zeineb Bakey, Oscar A. Cabrera, Julia Hoefele, Dinu Antony, Kaman Wu, Michael W. Stuck, Dimitra Micha, Thibaut Eguether, Abigail O. Smith, Nicole N. van der Wel, Matias Wagner, Lara I. Strittmatter, Philip L. Beales, Julie A. Jonassen, Isabelle Thiffault, , Gregory J. Pazour

This study identifies IFT74 variants causing skeletal ciliopathy and motile cilia defects in humans and mice, revealing functional differences between motile and primary cilia.

PLoS Genetics · Jun 14, 2023Peer-reviewedGenetic & Genomic Medicine

Base editing derived models of human WDR34 and WDR60 disease alleles replicate retrograde IFT and hedgehog signaling defects and suggest disturbed Golgi protein transport

Dinu Antony, Elif Yılmaz Güleç, Zeineb Bakey, Isabel Schüle, Gwang-Jin Kim, Ilona Skatulla, Han G. Brunner, Sebastian J. Arnold, Miriam Schmidts

bioRxiv · Mar 14, 2022 · PreprintGenetics

Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

Simon J. Haworth, Chin Yang Shapland, Caroline Hayward, Bram Peter Prins, Janine F. Felix, Carolina Medina‐Gómez, Fernando Rivadeneira, Carol A. Wang, Tarunveer S. Ahluwalia, Martine Vrijheid, Mònica Guxens, Jordi Sunyer, Ioanna Tachmazidou, Klaudia Walter, Valentina Iotchkova, , David K. Jackson

The paper identifies 9 novel genetic loci, including low-frequency variants in TP53, associated with head circumference and intracranial volume in up to 46,000 individuals.

Nature Communications · Jan 21, 2019Peer-reviewedGenetics