Author

Shazia Khan

University of Edinburgh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:ATAC-seq· 1 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Ruth AndrewiD· 3 shared Joanna P. SimpsoniD· 2 shared Natalie Z M HomeriD· 2 shared A Whittaker· 1 shared Adrian FreemaniD· 1 shared Ala HassounehiD· 1 shared Alex von Kreigsheim· 1 shared Alex von KriegsheimiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersBiochemistry

Ruth AndrewORCID

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Author profile →

4 papers

Recent·Most cited

Localisation of corticosteroids in male mouse kidney by mass spectrometry imaging

Ioannis Stasinopoulos, Shazia Khan, Shaden Melhem, Martin Roumain, Diego Cobice, Natalie Z M Homer, C. Logan Mackay, Roger Brown, Matthew A. Bailey, Ruth Andrew

This study uses mass spectrometry imaging to map corticosteroid distribution in mouse kidneys, revealing regional localization patterns and dietary salt effects on corticosterone levels.

Journal of Molecular Endocrinology · Jan 30, 2026Peer-reviewedBiochemistry

Enhancing Lipid Detection and Spatial Accuracy in Carotid Plaques Using Mass Spectrometry Imaging Techniques

Sphamandla Ntshangase, Sean McCafferty, Zahra Javid, Beth Whittington, Phyo H. Khaing, Tony Feng, Allison C. Winarski, Fraser Simpson, Shazia Khan, Joanna P. Simpson, Hannah O'Neill, Sharon Yen Ming Chan, Ala Hassouneh, Mark Davis, Rahul Velineni, , Ruth Andrew

This study improves MALDI-MSI sample preparation for carotid plaque lipid analysis by comparing methods, finding Cryofilm with sublimation best balances tissue preservation and lipid detection.

bioRxiv · Jan 14, 2026 · PreprintMolecular Biology

Pharmacological inhibition of 11βhydroxysteroid dehydrogenase type 1 after myocardial infarction targets extracellular matrix processing and preserves cardiac function in a translational mini-pig model

Sara Al Disi, Raimondo Ascione, Shazia Khan, TW Johnson, Eva C. Sammut, Vito Domenico Bruno, Daniel Baz-Lopez, Carol-Ann James, Joanna P. Simpson, Natalie Z M Homer, MIchael Millar, Trisha Singh, Alex von Kreigsheim, Nick L. Mills, B. S. Walker, , Gillian A. Gray

This study shows that inhibiting 11βHSD1 after myocardial infarction preserves cardiac function and prevents adverse remodelling in a mini-pig model.

British Journal of Pharmacology · Dec 28, 2025Peer-reviewedPharmacology & Toxicology

A bifunctional imprinted lncRNA scaffolds NuRD-HDAC1 to couple cis-activation of Dio3 with trans-repression of the osteoblast chromatin landscape

Yuechuan Chen, Benjamin Wildman, Mohammad Rehan, Snehasis Mishra, Shazia Khan, Lubana H. Afreen, Quamarul Hassan

The paper shows Dio3os scaffolds NuRD-HDAC1 to activate Dio3 in cis and repress thyroid-hormone-responsive osteogenic genes in trans.

bioRxiv · Apr 14, 2025 · PreprintMolecular Biology