Effects of P16 DNA Methylation on Proliferation, Senescence, and Lifespan of Human Fibroblasts
Ying Gan, Chenghua Cui, Shengyan Xiang, Baozhen Zhang, Dajun Deng
This study shows that P16 DNA methylation prevents senescence, promotes proliferation, and extends lifespan in human fibroblasts, potentially contributing to cancer development.
bioRxiv · Aug 30, 2018 · PreprintCell Biology