Author

Chenghua Cui

Peking University Cancer Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Baozhen ZhangiD· 2 shared Dajun DengiD· 2 shared Ying GaniD· 2 shared Jing ZhouiD· 1 shared Liankun GuiD· 1 shared Paiyun Li· 1 shared Shengyan Xiang· 1 shared Sisi Qin· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMolecular Biology

Baozhen ZhangORCID

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2 papers

Recent·Most cited

Hydroxymethylated-P16 Allele Is Transcription-Inactive

Ying Gan, Paiyun Li, Xiao Han, Sisi Qin, Chenghua Cui, Zhaojun Liu, Jing Zhou, Liankun Gu, Zheming Lu, Baozhen Zhang, Dajun Deng

This study shows that hydroxymethylated P16 alleles are transcriptionally inactive, demonstrated through engineered P16-specific dioxygenase-induced hydroxymethylation and its effects on cell growth and migration.

bioRxiv · Apr 24, 2019 · PreprintMolecular Biology

Effects of P16 DNA Methylation on Proliferation, Senescence, and Lifespan of Human Fibroblasts

Ying Gan, Chenghua Cui, Shengyan Xiang, Baozhen Zhang, Dajun Deng

This study shows that P16 DNA methylation prevents senescence, promotes proliferation, and extends lifespan in human fibroblasts, potentially contributing to cancer development.

bioRxiv · Aug 30, 2018 · PreprintCell Biology