Author

Ying Gan

Peking University Cancer HospitalORCID 0000-0001-8393-6768Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Baozhen ZhangiD· 2 shared Chenghua Cui· 2 shared Dajun DengiD· 2 shared Jing ZhouiD· 1 shared Liankun GuiD· 1 shared Paiyun Li· 1 shared Shengyan Xiang· 1 shared Sisi Qin· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMolecular Biology

Baozhen ZhangORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintApr 24, 2019

Hydroxymethylated-P16 Allele Is Transcription-Inactive

Ying Gan, Paiyun Li, Xiao Han…·Dajun Deng

This study shows that hydroxymethylated P16 alleles are transcriptionally inactive, demonstrated through engineered P16-specific dioxygenase-induced hydroxymethylation and its effects on cell growth and migration.

1 citation

humanDNA methylation

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Cell BiologybioRxivPreprintAug 30, 2018

Effects of P16 DNA Methylation on Proliferation, Senescence, and Lifespan of Human Fibroblasts

Ying Gan, Chenghua Cui, Shengyan Xiang…·Dajun Deng

This study shows that P16 DNA methylation prevents senescence, promotes proliferation, and extends lifespan in human fibroblasts, potentially contributing to cancer development.

DOI 10.1101/405407

humanDNA methylation

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