Pregnancy reprograms the enhancer landscape of mammary epithelial cells and alters the response to cMYC-driven oncogenesis
Mary J. Feigman, Matthew A. Moss, Chen Chen, Samantha L. Cyrill, Michael Francis Ciccone, Wesley D. Frey, Shih Ting Yang, John Erby Wilkinson, Camila O. dos Santos
The paper investigates how pregnancy alters the enhancer landscape of mammary epithelial cells and affects their response to cMYC-driven oncogenesis, finding that post-pregnancy cells are resistant to cMYC-induced proliferation.
bioRxiv · May 20, 2019 · PreprintMolecular Biology