Chen Chen

Co-Conservation of Synaptic Gene Expression and Circuitry in Collicular Neurons

The paper compares the molecular and cellular organization of the superior colliculus across species, identifying conserved neuronal subtypes and synaptic genes while highlighting divergent ciliary genes and an inhibitory neuron subtype.

Parity-induced changes to mammary epithelial cells control NKT cell expansion and mammary oncogenesis

The paper shows pregnancy-induced changes in mammary epithelial cells lead to NKT cell expansion and promote mammary oncogenesis through CD1d expression.

Glutamatergic and GABAergic neuronal populations in thedorsolateral Periacqueductual Gray have differentfunctional roles in fear conditioning

The paper investigates the functional roles of glutamatergic and GABAergic neuronal populations in the dorsolateral periacqueductal gray during fear conditioning, finding that only glutamatergic neurons persist in responding to conditioned stimuli during retrieval.

A VTA GABAergic neural circuit mediates visually evoked innate defensive responses

This study identifies VTA GABAergic neurons as critical for visually evoked innate defensive behaviors in mice.

Pregnancy reprograms the enhancer landscape of mammary epithelial cells and alters the response to cMYC-driven oncogenesis

The paper investigates how pregnancy alters the enhancer landscape of mammary epithelial cells and affects their response to cMYC-driven oncogenesis, finding that post-pregnancy cells are resistant to cMYC-induced proliferation.

Characterization of glutamatergic VTA neural population responses to aversive and rewarding conditioning in freely-moving mice

This study investigates how glutamatergic VTA neurons respond to aversive and rewarding conditioning in mice, revealing distinct patterns during conditioning and retrieval phases.