Author

Michael Francis Ciccone

Cold Spring Harbor Laboratory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 3 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Organism:mouse· 4 Approach:statistical model· 4 Research Focus:gene regulatory network inference· 3 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Camila O. dos SantosiD· 4 shared John Erby WilkinsoniD· 3 shared Samantha L. CyrilliD· 3 shared Amritha Varshini Hanasoge SomasundaraiD· 2 shared Chen CheniD· 2 shared Deeptiman ChatterjeeiD· 2 shared Mary J. Feigman· 2 shared Matthew A. MossiD· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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4 shared papersDevelopmental Biology

Camila O. dos SantosORCID

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Author profile →

4 papers

Recent·Most cited

Host response during unresolved urinary tract infection alters mammary tissue homeostasis through collagen deposition and TIMP1

Samantha Henry, Steven Macauley Lewis, Samantha L. Cyrill, Mackenzie Kate Callaway, Deeptiman Chatterjee, Amritha Varshini Hanasoge Somasundara, Gina Jones, Xue‐Yan He, Giuseppina Caligiuri, Michael Francis Ciccone, Isabella Andrea Diaz, Amelia Aumalika Biswas, Evelyn Hernández, Taehoon Ha, John Erby Wilkinson, , Camila O. dos Santos

This study shows that unresolved urinary tract infection leads to mammary tissue changes via collagen deposition and TIMP1, mediated by systemic host response.

bioRxiv · Feb 5, 2024 · PreprintDevelopmental Biology

Single-cell transcription mapping of murine and human mammary organoids responses to female hormones

Jenelys Ruiz Ortiz, Steven Macauley Lewis, Michael Francis Ciccone, Deeptiman Chatterjee, Samantha Henry, Adam C. Siepel, Camila O. dos Santos

This study maps the transcriptional responses of murine and human mammary organoids to female hormones, revealing molecular dynamics across species.

Journal of Mammary Gland Biology and Neoplasia · Jan 30, 2024Peer-reviewedDevelopmental Biology

Parity-induced changes to mammary epithelial cells control NKT cell expansion and mammary oncogenesis

Amritha Varshini Hanasoge Somasundara, Matthew A. Moss, Mary J. Feigman, Chen Chen, Samantha L. Cyrill, Michael Francis Ciccone, Marygrace C. Trousdell, Macy Vollbrecht, Siran Li, Jude Kendall, Semir Beyaz, John Erby Wilkinson, Camila O. dos Santos

The paper shows pregnancy-induced changes in mammary epithelial cells lead to NKT cell expansion and promote mammary oncogenesis through CD1d expression.

Cell Reports · Dec 1, 2021Peer-reviewedDevelopmental Biology

Pregnancy reprograms the enhancer landscape of mammary epithelial cells and alters the response to cMYC-driven oncogenesis

Mary J. Feigman, Matthew A. Moss, Chen Chen, Samantha L. Cyrill, Michael Francis Ciccone, Wesley D. Frey, Shih Ting Yang, John Erby Wilkinson, Camila O. dos Santos

The paper investigates how pregnancy alters the enhancer landscape of mammary epithelial cells and affects their response to cMYC-driven oncogenesis, finding that post-pregnancy cells are resistant to cMYC-induced proliferation.

bioRxiv · May 20, 2019 · PreprintMolecular Biology