Author

Shiow J. Lin

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:eQTL / molecular QTL mapping· 1 Research Focus:fine-mapping· 1

Frequent Co-Authors

Michael A. ProvinceiD· 3 shared Michael R. BrentiD· 3 shared Joseph M. ZmudaiD· 2 shared Kaare ChristenseniD· 2 shared Mary Furlan FeitosaiD· 2 shared Mary K. WojczynskiiD· 2 shared Sandeep AcharyaiD· 2 shared Alexander M. KulminskiiD· 1 shared

Activity by Year

2024-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Michael A. ProvinceORCID

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3 papers

Recent·Most cited

Discovery of genomic and transcriptomic pleiotropy between kidney function and soluble receptor for advanced glycation end-products using correlated meta-analyses: The Long Life Family Study (LLFS)

Mary Furlan Feitosa, Shiow J. Lin, Sandeep Acharya, Bharat Thyagarajan, Mary K. Wojczynski, Allison L. Kuipers, Alexander M. Kulminski, Kaare Christensen, Joseph M. Zmuda, Michael R. Brent, Michael A. Province

The paper identifies pleiotropic genetic factors shared between kidney function and sRAGE using GWAS and TWAS in the LLFS cohort.

Aging Cell · Jun 26, 2024Peer-reviewedGenetic & Genomic Medicine

A Novel Gene ARHGAP44 for Longitudinal Changes in Glycated Hemoglobin (HbA1c) in Subjects without Type 2 Diabetes: Evidence from the Long Life Family Study (LLFS) and the Framingham Offspring Study (FOS)

Siyu Wang, Petra A. Lenzini, Bharat Thygarajan, Joseph Hyungwoo Lee, Badri Narayan Vardarajan, Anatoli I. Yashin, Iva Miljkovic, E. Warwick Daw, Shiow J. Lin, Gary J. Patti, Michael R. Brent, Joseph M. Zmuda, Thomas T. Perls, Kaare Christensen, Michael A. Province, Ping An

The paper identifies ARHGAP44 as a novel gene associated with longitudinal changes in HbA1c in non-diabetic individuals using linkage and sequence analysis from two studies.

bioRxiv · May 16, 2024 · PreprintGenetics

Multi-omics Integration Identifies Genes Influencing Traits Associated with Cardiovascular Risks: The Long Life Family Study

Sandeep Acharya, Shu Liao, Wooseok J. Jung, Yu Sung Kang, Vaha Akbary Moghaddam, Mary Furlan Feitosa, Mary K. Wojczynski, Shiow J. Lin, Jason A. Anema, Karen Schwander, Jeff O Connell, Michael A. Province, Michael R. Brent

The paper integrates multi-omics data to identify genes influencing cardiovascular risk traits in the Long Life Family Study, finding 64 significant genes and replicating 29 in the Framingham Heart Study.

medRxiv · Mar 4, 2024 · PreprintGenetic & Genomic Medicine