Joseph M. Zmuda

The paper examines the relationship between erythrocyte count and mortality in older adults, finding a critical threshold below which mortality risk sharply increases.

The paper identifies epistatic interactions between HK1 and GCK genes affecting HbA1c levels using Bayesian methods and confirms findings in independent studies.

This study evaluates polygenic risk scores (PRS) for predicting Alzheimer's disease risk in a cohort of families with exceptional longevity and finds limited predictive power due to population-specific genetic differences.

The paper identifies pleiotropic genetic factors shared between kidney function and sRAGE using GWAS and TWAS in the LLFS cohort.

The paper identifies ARHGAP44 as a novel gene associated with longitudinal changes in HbA1c in non-diabetic individuals using linkage and sequence analysis from two studies.

A GWAS identified 20 rare genetic variants associated with better processing speed in the Long Life Family Study, replicated in Danish twin cohorts.

The paper shows that gut microbiome uniqueness increases with age and predicts survival in humans.

This study identifies 15 genetic loci associated with muscle weakness in older adults through a large meta-analysis, revealing new pathways linked to aging and health outcomes.