Author

Shiuhwei Chen

The University of Texas Southwestern Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Genetics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Dae-Seok KimiD· 3 shared Megan VirostekiD· 3 shared Philipp E. SchereriD· 3 shared Toshiharu OnoderaiD· 3 shared Chanmin JoungiD· 2 shared Jan‐Bernd FunckeiD· 2 shared Joselin Velasco· 2 shared May-Yun Wang· 2 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenetics

Dae-Seok KimORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

ETP-Specific Knockout Mice Reveal Endotrophin as a Key Regulator of Kidney Fibrosis in Ischemia-Reperfusion Injury Models

Dae-Seok Kim, Jan‐Bernd Funcke, Shiuhwei Chen, Kyounghee Min, Toshiharu Onodera, Min Kim, Qian Lin, Chanmin Joung, Joselin Velasco, Megan Virostek, Katarzyna Walendzik, Chitkale Hiremath, Denise K. Marciano, Philipp E. Scherer

This study develops an ETP-specific knockout mouse model to demonstrate ETP's critical role in kidney fibrosis during ischemia-reperfusion injury.

Experimental & Molecular Medicine · Nov 7, 2025Peer-reviewedGenetics

Adipogenin Dictates Adipose Tissue Expansion by Facilitating the Assembly of a Dodecameric Seipin Complex

Chao Li, Xue‐Nan Sun, Jan‐Bernd Funcke, Lauri Vanharanta, Xavier Prasanna, Kaitlynn Gov, Yan Li, Megan Virostek, Chanmin Joung, Nolwenn Joffin, Kristiina Kanerva, Ábel Szkalisity, Waldemar Kulig, Leon Gabriel Straub, Shiuhwei Chen, , Philipp E. Scherer

This study identifies Adig as a regulator of lipid droplet formation by stabilizing the dodecameric seipin complex, leading to increased fat mass and thermogenesis in mice.

Science · Nov 6, 2025Peer-reviewedCell Biology

A comparison of adiponectin-deficient mice reveals the fundamental role of intracellular adiponectin

Toshiharu Onodera, Dae-Seok Kim, May-Yun Wang, Megan Virostek, Shiuhwei Chen, Zachary A. Kipp, Evelyn A. Bates, Yan Li, Clair Crewe, Chao Li, Xue‐Nan Sun, Qianbin Zhang, Mengle Shao, Jihoon Shin, Christine M. Kusminski, , Philipp E. Scherer

This study compares adiponectin-deficient mice to show that intracellular globular adiponectin regulates adipose tissue metabolism by modulating PPARγ activity.

bioRxiv · Jul 12, 2025 · PreprintPhysiology