Author

Lauri Vanharanta

University of HelsinkiORCID 0000-0002-7902-0009Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Elina IkoneniD· 2 shared Ábel SzkalisityiD· 1 shared Alessandra FerrariiD· 1 shared Alexander NguyeniD· 1 shared Andrea R. NawrockiiD· 1 shared Andrew P. BeckeriD· 1 shared Ayanna Cobb· 1 shared Chanmin JoungiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Elina IkonenORCID

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2 papers

Recent·Most cited

Adipogenin Dictates Adipose Tissue Expansion by Facilitating the Assembly of a Dodecameric Seipin Complex

Chao Li, Xue‐Nan Sun, Jan‐Bernd Funcke, Lauri Vanharanta, Xavier Prasanna, Kaitlynn Gov, Yan Li, Megan Virostek, Chanmin Joung, Nolwenn Joffin, Kristiina Kanerva, Ábel Szkalisity, Waldemar Kulig, Leon Gabriel Straub, Shiuhwei Chen, , Philipp E. Scherer

This study identifies Adig as a regulator of lipid droplet formation by stabilizing the dodecameric seipin complex, leading to increased fat mass and thermogenesis in mice.

Science · Nov 6, 2025Peer-reviewedCell Biology

Cholesterol binding to VCAM-1 promotes vascular inflammation

John Paul Kennelly, Xiao Xu, Yajing Gao, Su Min Kim, Soon‐Gook Hong, Miranda Villanueva, Alessandra Ferrari, Lauri Vanharanta, Alexander Nguyen, Rohith T. Nagari, Nikolas R. Burton, Marc J. Tol, Andrew P. Becker, Min Jae Lee, Elina Ikonen, , Peter Tontonoz

The paper identifies cholesterol binding to VCAM-1 as a mechanism promoting vascular inflammation by stabilizing VCAM-1 and enhancing immune cell recruitment.

bioRxiv · Sep 17, 2024 · PreprintPhysiology