Author

Sienna B Sewell

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Julian N Sackey· 2 shared Robert W. GereauiD· 2 shared Vijay K. SamineniiD· 2 shared Alexander G. ChamessianiD· 1 shared Bo ZhangiD· 1 shared Bryan A. CopitsiD· 1 shared Christian E. PederseniD· 1 shared Edem S Ankudey· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersNeuroscience

Julian N Sackey

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2 papers

Recent·Most cited

Central Amygdala Neuronal Ensembles Coordinate Visceral Pain and Its Affective Behaviors

Vijay K. Samineni, Julian N Sackey, Junnan Li, Lite Yang, Alexander G. Chamessian, Sienna B Sewell, Hannah Hahm, Yufen Zhang, Bo Zhang, Robert W. Gereau

The paper identifies CeA neuronal ensembles that modulate visceral pain and its affective behaviors through optogenetic manipulation and single-nucleus RNA sequencing.

bioRxiv · Jul 21, 2025 · PreprintNeuroscience

Cellular, Circuit and Transcriptional Framework for Modulation of Itch in the Central Amygdala

Vijay K. Samineni, Jose G. Grajales‐Reyes, Gary E. Grajales‐Reyes, Eric Tycksen, Bryan A. Copits, Christian E. Pedersen, Edem S Ankudey, Julian N Sackey, Sienna B Sewell, Michael R. Bruchas, Robert W. Gereau

This study identifies itch-activated neurons in the central amygdala (CeA) and their role in itch sensation, avoidance, and comorbidities like anxiety, using RNA-sequencing and viral tracing.

eLife · May 25, 2021Peer-reviewedNeuroscience