Jose G. Grajales‐Reyes

This study identifies a novel target for obesity treatment by showing that inhibiting GABAergic neurons in the dorsal raphe nucleus reduces body weight in diet-induced obese mice through thermogenesis.

This study shows that early exposure to a Western diet in female mice leads to severe retinal and neurovascular issues, including anophthalmia and cataracts, highlighting the need for early intervention.

This study identifies itch-activated neurons in the central amygdala (CeA) and their role in itch sensation, avoidance, and comorbidities like anxiety, using RNA-sequencing and viral tracing.

This study identifies PAG neuronal populations that modulate acute and chronic itch by differentially regulating sensory and affective components through GABAergic and glutamatergic activity.

This study uses optogenetic inhibition of Nav1.8+ bladder sensory afferents in a mouse model of cystitis to reduce pain and hypersensitivity.