June Ereño‐Orbea

This study identifies CD11b as a noncanonical marker of cytotoxic competence in CD8+ T cells, enhancing their antitumor activity in mouse and human tumors.

This paper discovers non-carbohydrate inhibitors of Siglec-7:GD3 interactions using BiGEL libraries and validates their potency through SPR, ELISA, and NMR.

This study identifies CD24 as an innate immune checkpoint in colorectal cancer that promotes tumor survival by inhibiting macrophage-mediated clearance, validated through zebrafish models and human data.

This study identifies key residues in Siglec-10 involved in ligand recognition and shows that antibody blockade can restore CAR-T cell cytotoxicity.

This study shows that loss of UFMylation promotes prostate cancer metastasis by reprogramming glucose metabolism towards hexosamine biosynthesis.

The paper investigates SARS-CoV-2 infection in the hypothalamus and associated regions, showing viral entry receptors and susceptibility factors linked to neurological symptoms in COVID-19.