Author

Ana Gimeno

IkerbasqueORCID 0000-0001-9668-2605Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Approach:deep learning· 1 Organism:E. coli· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Edward N. SchmidtiD· 2 shared Jesús Jiménez‐BarberoiD· 2 shared June Ereño‐OrbeaiD· 2 shared A. Michael DowneyiD· 1 shared Alexandre BoschiD· 1 shared Amaia MentxakaiD· 1 shared Anna M. EhlersiD· 1 shared Antonio FranconettiiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiochemistry

Edward N. SchmidtORCID

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3 papers

Recent·Most cited

BiochemistryJournal of the American Chemical SocietyPeer-reviewedSep 9, 2026

Non-Carbohydrate Inhibitors of Sialic Acid-binding Immunomodulatory-type Lectin-7 (Siglec-7) Discovered from Genetically Encoded Bicyclic Peptide Libraries

Danial Yazdan, A. Michael Downey, Ana Gimeno…·Ratmir Derda

This paper discovers non-carbohydrate inhibitors of Siglec-7:GD3 interactions using BiGEL libraries and validates their potency through SPR, ELISA, and NMR.

DOI 10.1021/jacs.6c14068

proteomicsdeep learning

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Molecular BiologybioRxivPreprintJun 10, 2025

Molecular basis of Siglec-10 ligand recognition and antibody blockade

Klaudia Sobczak, Asier Antoñana-Vildosola, Pablo Valverde…·June Ereño‐Orbea

This study identifies key residues in Siglec-10 involved in ligand recognition and shows that antibody blockade can restore CAR-T cell cytotoxicity.

6 citations

humanprotein structure

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BiochemistryJournal of the American Chemical SocietyPeer-reviewedDec 9, 2024

A Chemoenzymatic Strategy for Site-Specific Glyco-Tagging of Native Proteins for the Development of Biologicals

Ana Gimeno, Anna M. Ehlers, Sandra Delgado…·Geert‐Jan Boons

This paper develops a chemoenzymatic method to precisely glyco-tag proteins, enabling the modification of therapeutic proteins with diverse glycans while maintaining their biological activity.

14 citations

E. coliproteomics

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