Applying computational protein design to engineer affibodies for affinity-controlled delivery of vascular endothelial growth factor and platelet-derived growth factor
Justin E. Svendsen, Madeleine R. Ford, Chandler L. Asnes, Simon C. Oh, Jonathan Dorogin, Karly M. Fear, Johnathan R. O’Hara-Smith, Lauren O. Chisholm, Sophia R. Phillips, Michael J. Harms, Parisa Hosseinzadeh, Marian H. Hettiaratchi
This paper engineers affibodies with tunable affinities for VEGF and PDGF using computational design and yeast display to improve controlled protein release from hydrogels.
Biomacromolecules · May 9, 2025Peer-reviewedBioengineering