Author

Simone K. Benassi

Salk Institute for Biological Studies

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Lynne Randolph‐Moore· 2 shared Maria Carolina MarchettoiD· 2 shared Aidan H. McDonald· 1 shared Amandeep SharmaiD· 1 shared Amoolya Chandrabhatta· 1 shared Ana Paula Diniz Mendes· 1 shared Ariana L. Tucker· 1 shared Baptiste N. JaegeriD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersNeuroscience

Lynne Randolph‐Moore

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2 papers

Recent·Most cited

Human AUTS2 regulates neurodevelopmental pathways via dual DNA/RNA binding.

Verônica Monteiro Saia-Cereda, Amandeep Sharma, Keegan Flanagan, Sara Elmsaouri, Sheila Steiner, Simone K. Benassi, Guilherme Reis‐de‐Oliveira, Jack T. Whiteley, Amoolya Chandrabhatta, Ana Paula Diniz Mendes, Lynne Randolph‐Moore, Dimitra Xenitopoulos, Milla Jetzer, Ruth Oefner, Christopher W. Benner, , Maria Carolina Marchetto

This study identifies AUTS2's dual DNA/RNA binding in human neural progenitors and shows its role in regulating Wnt pathway genes, linking its disruption to neurodevelopmental disorders.

bioRxiv · Oct 7, 2025 · PreprintNeuroscience

CK2 inhibition suppresses glial inflammation in the brain

Ioana I. N. Da Silva, Desiree Ramirez, Sarah Parylak, Leslie A. Wallace, James K. Tucker, Joel M. Erberich, Rutvi Katariya, Aidan H. McDonald, Iryna S. Gallina, Ariana L. Tucker, Jillybeth Burgado, Baptiste N. Jaeger, Jerika J. Barron, Joshua M. Pratt, Monique Pena, , Fred H. Gage

This study identifies CK2 as a key driver of glial inflammation in neurodegenerative disorders and shows that its inhibition reduces inflammation in AD models.

bioRxiv · Aug 5, 2025 · PreprintNeuroscience