Author

Simone Lang

F. Hoffmann-La Roche AG

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:dimensionality reduction· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Adriano BerniniiD· 1 shared Ahmet VaroliD· 1 shared Andreas HugiD· 1 shared Antoine LuttiiD· 1 shared Aparna Neelakandhan· 1 shared Christian KleiniD· 1 shared Christian MünziD· 1 shared Dario Venetz· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Adriano BerniniORCID

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2 papers

Recent·Most cited

Chronic Antigen Stimulation in Solid Tumors Induces T Cell Exhaustion and Limits Efficacy of T Cell Bispecific Therapies

Idil Hutter-Karakoc, Eleni Maria Varypataki, Aparna Neelakandhan, Simone Lang, Vesna Kramar, Ahmet Varol, Sasha Simons, Marine Richard, Mudita Pincha, Dario Venetz, Nicole Joller, Christian Münz, Pablo Umaña, Christian Klein, Maria Amann

This study shows that chronic antigen exposure leads to T cell exhaustion, reducing the effectiveness of T cell bispecific therapies in solid tumors.

bioRxiv · Jan 29, 2025 · PreprintCancer Biology

Brain tissue properties and morphometry assessment after chronic complete spinal cord injury

Andreas Hug, Adriano Bernini, Haili Wang, Antoine Lutti, Johann M. E. Jende, Markus Böttinger, Marc‐André Weber, Norbert Weidner, Simone Lang

This study assesses brain tissue properties and morphometry in chronic complete spinal cord injury patients using MRI, finding significant white matter volume loss linked to Wallerian degeneration but no structural brain changes with conventional analysis.

bioRxiv · Feb 15, 2019 · PreprintNeuroscience