Author

Siyu Chen

Children's Hospital of Chongqing Medical University

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Biology Disciplines

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Developmental Biology· 1 Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Carolina Mendez· 1 shared Dengchang Wu· 1 shared Di WuiD· 1 shared Diana Atlas· 1 shared Fangcong DongiD· 1 shared Gabriel E. ValdebenitoiD· 1 shared Gary J. PattiiD· 1 shared Hao Zhang· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperDevelopmental Biology

Carolina Mendez

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Author profile →

3 papers

Recent·Most cited

A genetically encoded redox bottleneck constrains human developmental rate

Gabriel E. Valdebenito, Jack P. Madden, Carolina Mendez, Leslie M. Azurdia, Xintao Zhu, Siyu Chen, Diana Atlas, Katherine Introcaso, Hao Zhang, 亚辉王, Fangcong Dong, Rohit Sharma, Vamsi Krishna Mootha, Gary J. Patti, Margarete Díaz-Cuadros

This paper identifies a genetic bottleneck in the G3P shuttle that limits human developmental rate by constraining metabolic flux and the segmentation clock.

bioRxiv · Sep 13, 2026 · PreprintDevelopmental Biology

Hyperactive STAT1 Promotes T Follicular Helper Type 1 Cell Differentiation to Trigger Autoimmunity

Ran Chen, Xuemei Chen, Jigui Yang, Huilin Mu, Shengqiao Mao, Siyu Chen, Rui Gan, Qinglv Wei, Wenjing Tang, Junfeng Wu, Wuyang He, Satoshi Okada, Lina Zhou, 安云飞, Xiaodong Zhao, Yanjun Jia

Overactivated STAT1 promotes Tfh1 differentiation to drive autoimmunity.

Journal of Allergy and Clinical Immunology · Sep 1, 2026Peer-reviewedImmunology

Towards Unified Neural Decoding with Brain Functional Network Modeling

Di Wu, Linghao Bu, Yifei Jia, Lu Cao, Siyuan Li, Siyu Chen, Yueqian Zhou, Sheng Fan, Wenjie Ren, Dengchang Wu, Kang Wang, Yue Zhang, Yuehui Ma, Jie Yang, Mohamad Sawan

This paper introduces MIBRAIN, a framework for interindividual neural decoding using brain functional network modeling, showing improved decoding accuracy with multi-subject data integration.

bioRxiv · Jun 2, 2025 · PreprintNeuroscience