Author

Satoshi Okada

Hiroshima UniversityORCID 0000-0002-4622-5657Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Satoshi Okada1 paper · Okayama University

Biology Disciplines

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Genetics· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Aayushee JainiD· 1 shared Achim A WerneriD· 1 shared Anne PueliD· 1 shared Anthony J. AsmariD· 1 shared Apratim MitraiD· 1 shared Avner SchlessingeriD· 1 shared Çiğdem Sevim BayrakiD· 1 shared Cynthia J. TifftiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperGenetics

Aayushee JainORCID

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3 papers

Recent·Most cited

Hyperactive STAT1 Promotes T Follicular Helper Type 1 Cell Differentiation to Trigger Autoimmunity

Ran Chen, Xuemei Chen, Jigui Yang, Huilin Mu, Shengqiao Mao, Siyu Chen, Rui Gan, Qinglv Wei, Wenjing Tang, Junfeng Wu, Wuyang He, Satoshi Okada, Lina Zhou, 安云飞, Xiaodong Zhao, Yanjun Jia

Overactivated STAT1 promotes Tfh1 differentiation to drive autoimmunity.

Journal of Allergy and Clinical Immunology · Sep 1, 2026Peer-reviewedImmunology

Identification of Discriminative Gene-level and Protein-level Features Associated with Gain-of-Function and Loss-of-Function Mutations

Çiğdem Sevim Bayrak, Aayushee Jain, David F. Stein, Kumardeep Chaudhary, Girish N. Nadkarni, Tielman T. Van Vleck, Anne Puel, Stéphanie Boisson‐Dupuis, Satoshi Okada, Peter D. Stenson, D.N. Cooper, Avner Schlessinger, Yuval Itan

The paper identifies gene- and protein-level features distinguishing gain-of-function and loss-of-function mutations using NLP and machine learning on a new database of pathogenic mutations.

bioRxiv · Jan 1, 2021 · PreprintGenetics

Regulation of human development by ubiquitin chain editing of chromatin remodelers

David B. Beck, Mohammed Abul Basar, Anthony J. Asmar, Joyce J. Thompson, Hirotsugu Oda, Daniela Tiaki Uehara, Ken Saida, Precilla D’Souza, Joann Norma Bodurtha, Weiyi Mu, Kristin W. Baranano, Noriko Miyake, Raymond Wang, Marlies J. E. Kempers, Yutaka Nishimura, , Achim A Werner

This study identifies OTUD5 as essential for chromatin remodeling during development, showing its role in preventing degradation of chromatin regulators and maintaining proper gene expression networks.

bioRxiv · Jan 23, 2020 · PreprintGenetics