Author

Rui Gan

Children's Hospital of Chongqing Medical UniversityPrimary ORCID profile (0000-0002-1214-6002 · 5 papers)Unclaimed ORCID profile · follow to get notified of new preprints

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Rui GaniD5 papers · Harbin Institute of Technology

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Immunology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein design· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrej LuptákiD· 1 shared Barbara L. GoldeniD· 1 shared Bo ZhuiD· 1 shared Chen JiiD· 1 shared Donald H. BurkeiD· 1 shared Gerald Manuel· 1 shared Hideo NakanoiD· 1 shared Hillary Andaluz Aguilar· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

Andrej LuptákORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Engineering a ribozyme with aminoacyl-tRNA synthetase activity

Rui Gan, Chen Ji, Gerald Manuel, Hillary Andaluz Aguilar, W. Andy Tao, Robert M. Corn, Donald H. Burke, Andrej Lupták, Barbara L. Golden

This paper engineers a ribozyme that can aminoacylate tRNA and discriminate between cognate and non-cognate tRNAs, enabling non-canonical amino acid incorporation.

ACS Chemical Biology · Sep 26, 2026Peer-reviewedBiochemistry

Hyperactive STAT1 Promotes T Follicular Helper Type 1 Cell Differentiation to Trigger Autoimmunity

Ran Chen, Xuemei Chen, Jigui Yang, Huilin Mu, Shengqiao Mao, Siyu Chen, Rui Gan, Qinglv Wei, Wenjing Tang, Junfeng Wu, Wuyang He, Satoshi Okada, Lina Zhou, 安云飞, Xiaodong Zhao, Yanjun Jia

Overactivated STAT1 promotes Tfh1 differentiation to drive autoimmunity.

Journal of Allergy and Clinical Immunology · Sep 1, 2026Peer-reviewedImmunology

Increasing cell-free gene expression yields from linear templates in Escherichia coli and Vibrio natriegens extracts by using DNA-binding proteins

Bo Zhu, Rui Gan, Maria D. Cabezas, Takaaki Kojima, Robert Nicol, Michael C. Jewett, Hideo Nakano

This paper introduces a method to increase gene expression from linear DNA templates in cell-free systems by using DNA-binding proteins, achieving significant yield improvements in both E. coli and Vibrio natriegens.

Biotechnology and Bioengineering · Aug 20, 2020Peer-reviewedSynthetic Biology