Author

Skyler Demis

Marquette University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:cell type annotation· 3 Assay:electronic health records· 3 Approach:experimental assay· 3 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

Frequent Co-Authors

Annabel EngelhardtiD· 4 shared Eden M. Anderson· 4 shared Matthew C. HearingiD· 4 shared Aric MadayagiD· 1 shared Benjamin WruckeiD· 1 shared Elissa Porath· 1 shared Evan M. HessiD· 1 shared Hunter D’Acquisto· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersNeuroscience

Annabel EngelhardtORCID

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4 papers

Recent·Most cited

Remifentanil self-administration promotes circuit- and sex-specific adaptations within the prefrontal-accumbens pathways

Saurabh S. Kokane, Shalana I. Atwell, Aric Madayag, Eden M. Anderson, Skyler Demis, Annabel Engelhardt, Logan Friedrich, Matthew C. Hearing

This study investigates sex- and pathway-specific synaptic adaptations in mPFC-NAc circuits following remifentanil self-administration and abstinence, revealing differences in AMPA/NMDA ratios and presynaptic signaling.

Frontiers in Cellular Neuroscience · May 8, 2026Peer-reviewedNeuroscience

Suppression of pyramidal neuron G protein-gated inwardly rectifying K+ channel signaling impairs prelimbic cortical function and underlies stress-induced deficits in cognitive flexibility

Eden M. Anderson, Steven Loke, Benjamin Wrucke, Annabel Engelhardt, Skyler Demis, Kevin O’Reilly, Evan M. Hess, Kevin D. Wickman, Matthew C. Hearing

This study shows that GIRK channel signaling in male mice is critical for prelimbic cortical function and stress-induced cognitive flexibility, but not in females.

Neuropsychopharmacology · Jun 22, 2021Peer-reviewedNeuroscience

The role of parvalbumin interneuron GIRK signaling in regulation of affect and cognition inmale and female mice

Eden M. Anderson, Skyler Demis, Hunter D’Acquisto, Annabel Engelhardt, Matthew C. Hearing

This study investigates the role of parvalbumin interneuron GIRK signaling in affect and cognition in male and female mice, finding sex-specific effects on behavior and neuronal firing.

Frontiers in Behavioral Neuroscience · Mar 26, 2021Peer-reviewedNeuroscience

Sex-specific prefrontal cortex dysfunction underlying opioid-induced cognitive impairment

Eden M. Anderson, Annabel Engelhardt, Skyler Demis, Elissa Porath, Matthew C. Hearing

This study identifies sex-specific synaptic changes in the prefrontal cortex that underlie opioid-induced cognitive impairment and suggests sex-based interventions for addiction treatment.

bioRxiv · Jul 2, 2020 · PreprintNeuroscience