Author

Jocelyn Charlton

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Abdelkader Essafi· 1 shared Aharon HelmaniD· 1 shared Alex von KriegsheimiD· 1 shared Alexander MeissneriD· 1 shared Debasis Mohapatra· 1 shared Douglas A. MeltoniD· 1 shared Giulia Petrovich· 1 shared Iwin Joseph· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Abdelkader Essafi

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2 papers

Recent·Most cited

Tumour suppressor WT1 and its interacting protein RNA helicase DDX5 regulate the microRNA let7/Igf1r axis in the kidney mesenchyme

Sourav Dey, Joan Slight, Stuart Aitken, Iwin Joseph, Utkarsh Bhore, Alex von Kriegsheim, Giulia Petrovich, Jocelyn Charlton, Viktoriya G. Stancheva, Debasis Mohapatra, Abdelkader Essafi, Kathy Pritchard‐Jones, Nicholas Dixon Hastie, Ruthrothaselvi Bharathavikru

The paper shows WT1 and DDX5 regulate the let7/Igf1r axis in kidney mesenchyme, linking WT1 mutations to Wilms Tumour through microRNA and IGF signalling pathways.

bioRxiv · Jan 5, 2025 · PreprintCancer Biology

Dissecting mechanisms of human islet differentiation and maturation through epigenome profiling

Juan R. Alvarez‐Dominguez, Julie Donaghey, Niloofar Rasouli, Jennifer Hyoje-Ryu Kenty, Aharon Helman, Jocelyn Charlton, Juerg Straubhaar, Alexander Meissner, Douglas A. Melton

This study profiles the epigenome during human islet differentiation, revealing epigenetic priming of lineage-defining loci and the role of LMX1B in endocrine progenitor regulation.

Cell stem cell · Dec 12, 2019Peer-reviewedGenomics