Reevaluating the Role of Beta2-Microglobulin: New Insights on Selective Vulnerability in ALS Pathology
Mélanie Lebœuf, Jik Nijssen, Laura Helen Comley, Julio Cesar Aguila Benitez, Irene Mei, Silvia Gómez Alcalde, Ramón A. Muñoz de Bustillo Alfaro, Vlad Radoi, Susanne Nichterwitz, Christoph Schweingruber, Abraham Acevedo‐Arozena, Eva Hedlund, Staffan Cullheim
This study investigates the role of beta2-microglobulin and HLA in motor neuron vulnerability in ALS, finding dynamic regulation but not major disease modification.
Acta Neuropathologica · May 29, 2026Peer-reviewedNeuroscience