Author

Vlad Radoi

Stockholm UniversityORCID 0000-0002-9657-8303Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Christoph SchweingruberiD· 2 shared Eva HedlundiD· 2 shared Irene MeiiD· 2 shared Jik NijsseniD· 2 shared Mélanie LebœufiD· 2 shared Abraham Acevedo‐ArozenaiD· 1 shared Erin C. HedgesiD· 1 shared Jonas MechtersheimeriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersNeuroscience

Christoph SchweingruberORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Reevaluating the Role of Beta2-Microglobulin: New Insights on Selective Vulnerability in ALS Pathology

Mélanie Lebœuf, Jik Nijssen, Laura Helen Comley, Julio Cesar Aguila Benitez, Irene Mei, Silvia Gómez Alcalde, Ramón A. Muñoz de Bustillo Alfaro, Vlad Radoi, Susanne Nichterwitz, Christoph Schweingruber, Abraham Acevedo‐Arozena, Eva Hedlund, Staffan Cullheim

This study investigates the role of beta2-microglobulin and HLA in motor neuron vulnerability in ALS, finding dynamic regulation but not major disease modification.

Acta Neuropathologica · May 29, 2026Peer-reviewedNeuroscience

Single-cell RNA sequencing across isogenic FUS and TARDBP ALS lines reveals a shared early mitochondrial dysfunction unique to motor neurons.

Christoph Schweingruber, Jik Nijssen, Jonas Mechtersheimer, Stefan Reber, Mélanie Lebœuf, Niamh Louise O’Brien, Irene Mei, Erin C. Hedges, Michaela Keuper, Julio Aguila Benitez, Vlad Radoi, Martin Jastroch, Marc‐David Ruepp, Eva Hedlund

This study uses single-cell RNA sequencing to identify shared mitochondrial dysfunction in motor neurons across FUS and TARDBP ALS mutations, suggesting common toxic mechanisms.

Nature Communications · May 19, 2025Peer-reviewedNeuroscience