Author

Stephen C. Kneeland

Jackson Laboratory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Andrew Phillip WestiD· 1 shared Brian Robert HoffmanniD· 1 shared Camila Guerra MartineziD· 1 shared Carolyn L. CannoniD· 1 shared Jessica K. WongiD· 1 shared Jordyn J. VanPortflietiD· 1 shared Kathryn M. PflugiD· 1 shared Muthumeena RamanathaniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Andrew Phillip WestORCID

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Author profile →

1 paper

Recent·Most cited

Caspase-11 drives macrophage hyperinflammation in models of Polg-related mitochondrial disease

Jordyn J. VanPortfliet, Yuanjiu Lei, Muthumeena Ramanathan, Camila Guerra Martinez, Jessica K. Wong, Timothy J. Stodola, Brian Robert Hoffmann, Kathryn M. Pflug, Raquel Sitcheran, Stephen C. Kneeland, Stephen A. Murray, Peter J. McGuire, Carolyn L. Cannon, Andrew Phillip West

This study identifies caspase-11 as a driver of macrophage hyperinflammation in Polg-related mitochondrial disease models, linking IFN-I signaling to exacerbated infection outcomes.

Nature Communications · May 20, 2025Peer-reviewedImmunology