Myosin-9b Controls Epithelial Brush Border Architecture through Motility-Dependent RhoA Signaling
Emma C. Murray, Namya Manoj, Lynn M. Ziegler, Gillian M. Hodge, Shane Fraher, Leighton S. Lee, Lucas Code, Steven A. Lewis, Christine E. Schaner Tooley, Yongho Bae, John Konen, Jonathan Bard, Andrew T. Lombardo
This study identifies Myo9b's role in regulating epithelial brush border microvilli through RhoA signaling and shows that a disease variant disrupts microvilli formation in human cells.
bioRxiv · Sep 11, 2026 · PreprintCell Biology