Author

Shane Fraher

University at Buffalo, State University of New York

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Christine E. Schaner TooleyiD· 3 shared Andrew T. LombardoiD· 2 shared Emma C. Murray· 2 shared Gillian M. Hodge· 2 shared Leighton S. Lee· 2 shared Namya ManojiD· 2 shared Yongho BaeiD· 2 shared Cameron A.R. Mitchell· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCell Biology

Christine E. Schaner TooleyORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Myosin-9b Controls Epithelial Brush Border Architecture through Motility-Dependent RhoA Signaling

Emma C. Murray, Namya Manoj, Lynn M. Ziegler, Gillian M. Hodge, Shane Fraher, Leighton S. Lee, Lucas Code, Steven A. Lewis, Christine E. Schaner Tooley, Yongho Bae, John Konen, Jonathan Bard, Andrew T. Lombardo

This study identifies Myo9b's role in regulating epithelial brush border microvilli through RhoA signaling and shows that a disease variant disrupts microvilli formation in human cells.

bioRxiv · Sep 11, 2026 · PreprintCell Biology

The Rho effector ARHGAP18 coordinates a Hippo pathway feedback loop through YAP and Merlin to regulate the cytoskeleton and epithelial cell polarity.

Emma C. Murray, Gillian M. Hodge, Khanh Pham, Shane Fraher, Leighton S. Lee, Cameron A.R. Mitchell, Namya Manoj, Christine E. Schaner Tooley, Yongho Bae, Andrew T. Lombardo

This study identifies ARHGAP18 as a RhoA effector that forms a complex with YAP to coordinate Hippo and Rho pathways in regulating actin cytoskeleton and epithelial polarity.

Molecular Biology of the Cell · May 13, 2026Peer-reviewedCell Biology

Neuroinflammation links the neurogenic and neurodegenerative phenotypes of Nrmt1-/- mice

James P. Catlin, Shane Fraher, Jessy John Alexander, Christine E. Schaner Tooley

This study shows that Nrmt1-/- mice exhibit premature aging and neurodegeneration linked to neuroinflammation due to impaired neurogenesis and lack of anti-inflammatory response.

bioRxiv · Sep 2, 2025 · PreprintNeuroscience